In this article research findings are presented and discussed on the persistente of change in patients after termination of intensive psychotherapeutic treatment in a residential setting. Follow-up assessments at one and three years after discharge produced data on the psychological condition of the subjects in terms of general well-being that were related to similar assessments that were performed at the beginning of the treatment as well as at discharge. Pre-, post- and follow-up data indicate a significant elevation of the level of general well-being with a major progression during the episode between the beginning and the termination of treatment. The follow-up assessments showed a slighter but nevertheless significant further improvement as well. Additional analysis was done to explicitate the influence of factors such as sex, diagnostic category and duration of treatment on therapy-results. These findings give lead to interesting and promising hypotheses on factors that either facilitate or frustrate the efficacy of residential psychotherapy.