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Tijdschrift voor Psychiatrie 52 (2010) 4, 259 - 263

Case report

Dopamine dysregulation syndrome in a patient with Parkinson's disease

W.M. Hol, R. van der Zwaard, A. Hovestadt, H.J.G.M. van Megen

Both Parkinson's disease and its treatment can be associated with psychiatric symptoms. We illustrate this link by focusing on a patient suffering from Parkinson's who received not only deep brain stimulation but also excessive amounts of dopaminergic drugs, a combination that resulted in hypomania which is also known as dopamine dysregulation syndrome. We discuss the symptoms, possible aetiological pathways and the implications for clinical practice.

keywords addiction, dopamine dysregulation, Parkinson disease