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Omslag 2020 10 kijk verder

Tijdschrift voor Psychiatrie 38 (1996) 11

New research

Psychosis as a late symptom in Velo-cardio-facial syndrome

G.M. Lemmens, S. Claes, K. Devriendt

Velo-cardio-facial syndrome (VCFS) is acongenital malformation syndrome of vari-able clinical expression. The syndrome s major features are cleft palate, cardiac anomalies, characteristic facies, and learning disabilities. Recently, psychiatric disorders have been reported in over 10% of patients with VCFS. We report a schizophrenic woman with features of VCFS and detection of a 22q11 deletion. This observation suggests that VCFS and certain psychotic disorders may share a similar pathogenic mechanism.