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Tijdschrift voor Psychiatrie 48 (2006) 6, 481 - 485

Case report

Breast cancer in the family; a possible contra-indication to the use of dopamine antagonists. A case study

M.A.C. Nijpels, E. Harnisch, C.M.T. Gijsbers van Wijk

A 23-year-old woman with a family history of breast cancer suffers from a psychotic disorder and has symptoms of anxiety and depression. There are some indications in the literature that the use of dopamine antagonists can lightly increase the risk of developing breast cancer. So far there is insufficient scientific evidence to justify alterations in the standard treatment strategy simply on the grounds that a woman has a family history of breast cancer. We do however recommend that women in this risk category be tested periodically for possible breast cancer.

keywords antipsychotic agents, breast neoplasms, hyperprolactinemia