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Tijdschrift voor Psychiatrie 40 (1998) 8, 460 - 468

New research

Cognitive side-effects of lithium; a meta-analysis and proposal for screening

B.M.G. Arts, A. Honig, W.J. Riedel, R.H.W.M. Ponds

In this study a meta-analysis is presented of the literature concerning cognitive effects of lithium in patients with bipolar disorder. Lithium has a detrimental effect on memory and speed of information-processing. This may have negative consequences for daily functioning, e.g. driving. At the end we make some recommendations for testing the effects of lithium on cognition in daily practice.

keywords cognition, bipolar disorder, lithium