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Tijdschrift voor Psychiatrie 61 (2019) 1, 48 - 52

Klinische Praktijk

Psychosis due to idiopathic basal ganglia calcification

N. Levina, F. Maes, B.G.C. Sabbe

Idiopathic basal ganglia calcification is a rare neuropathological syndrome characterised by symmetrical and bilateral calcifications found primarily in the basal ganglia. Psychosis is describedas an acute presentation of idiopathic ganglia calcification. We describe the development of psychosis in a 48-year-old man, initially hospitalised on the neurology ward due to syncope. A ct scan of the brain showed bilateral, symmetrical calcification of the basal ganglia and nucleus dentatus. Laboratory research excluded other pathological disorders. The patient was referred to a psychiatric ward, where the administration of risperidone led to alleviation of his mental state. This case report underlines the importance of an accurate, comprehensive differential diagnosis and the associated significance of neuroimaging.

keywords basal ganglia, idiopathic basal ganglia calcification, psychosis