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Tijdschrift voor Psychiatrie 43 (2001) 6, 411 - 415

Short report

Mood disorders as risk factor for ischemic heart disease

M.J.A.M. Coopmans

Recent prospective cohort studies indicate mood disorders to be an independent risk factor for the development of ischemic heart disease many years later. The main hypotheses to explain this risk are a hypothalamic-pituitary-adrenocortical hyperactivity and a decreased heart rate variability that have been found in many depressed patients. The preventive importance of an adequate treatment of depression and cardiac screening in case of a history of depression, is stressed.

keywords ischemic heart disease, mood disorder, systematic review