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Tijdschrift voor Psychiatrie 48 (2006) 5, 399 - 404

Case report

A cocaine-induced variant of the neuroleptic malignant syndrome. A case study

M.H. Smidt, E.C.A. Collumbien

In this article we discuss the case of a patient with schizophrenia who presented with the clinical symptoms of coma, fever and rigidity. Initially it was suspected that the patient had a neuroleptic malignant syndrome. Closer inspection revealed that the patient had recently used cocaine. It is known that cocaine can cause a variant of the neuroleptic malignant syndrome. The patient was treated with dantrolene sodium and bromocriptine in the Intensive Care Unit and made a complete recovery within four days.

keywords cocaine, neuroleptic malignant syndrome, variant